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Best Antihistamine For Cat Allergies

Best Antihistamine For Cat Allergies

Key Points On Immunotherapy

Immunotherapy is also known as Hyposensitization Therapy or Allergy Vaccine. It involves the administration of subcutaneous injections or drops to increase the doses.

  • Formulating allergens depends on whether intradermal skin tests or serologic tests are performed in conjunction with the history of the cat, which includes seasonal flares.
  • ASIT’s mechanism of action is not known. Most hypotheses indicate that the introduction of proteins tested as allergens in dilute but increasing quantities results in tolerance, and eventually a decrease in clinical symptoms.
  • The time it takes to observe a cat’s response to ASIT will vary from one patient to the next. Some cats respond in just a few months while others take several months. Owners are advised to keep ASIT going for at least one year, before fully assessing the benefits.
  • To achieve maximum success, follow-up is crucial. Client education and compliance are key. Owners should be taught to recognize patterns and levels of pruritus, as well as adverse reactions.
  • Adverse reactions are typically mild and uncommon, but can include intensification of clinical signs for a few hours or days post injection, local reactions at the injection site, or rarely, anaphylaxis.
  • Escalation in pruritus may indicate that the atopic cat has reached its maximum tolerance dose of antigen.

Comparative Studies with Other Allergy Medicines

Antihistamines are constantly being studied, improved, and compared by researchers. Benadryl and Allegra are two other popular brands currently on the market.

  • Allegra is a medication that contains the active ingredient, fexofenadine. Allegra is non-sedating, so it should not make a person feel drowsy. Allegra is also a second-generation antihistamine.
  • Benadryl contains the active ingredient diphenhydramine. This acts faster than the other three and aims to treat minor skin reactions, not seasonal allergies. Benadryl, a first-generation antihistamine is considered sedating. People may feel sleepy upon taking it.

best antihistamine for cat allergies


Zyrtec and Claritin are brand-name medications that people can buy over the counter. They are available in various forms, including pills, chewable tablets, and syrups.

Regardless of marketing claims, little scientific evidence shows that either is more effective.

Active ingredients

Zyrtec and Claritin have different active compounds.

Zyrtec is made up of cetirizine hydrochloride (also known as cetirizine HPCL), while Claritin has loratadine.


Zyrtec and Claritin are second-generation antihistamines. They are less likely to make a person feel drowsy or otherwise affect alertness than older, first-generation antihistamines.

Zyrtec’s label states that it should be avoided when operating machinery or driving vehicles. People should avoid taking Zyrtec with alcohol or other medicines that could cause drowsiness.


Claritin and Zyrtec are both effective for approximately 24 hours. A person should only take one dose per day. Zyrtec works faster than the other antihistamines because it is absorbed quickly by your body.

A 2014 study found that both drugs were absorbed into the bloodstream within 1-2 hours of taking the medication.

What Are Allergies And How Do They Affect Cats?

Allergies are the most frequent medical condition that cats experience. An allergy occurs when the cat’s immune system overreacts or is hypersensitive to foreign substances called allergens. Allergens are simply foreign proteins that the body’s immune system tries to remove. Pollen, pet hair, dust and molds are all common allergens in humans. There are three possible ways hypersensitivity can occur in cats:

1. Itching is the most frequent manifestation. This can be localized or spread to the entire body.

2. The respiratory system can also be affected and could cause wheezing and sneezing. There may also be a nasal or eye discharge.

3. The third manifestation involves the digestive system and can result in vomiting, flatulence, and/or diarrhea.

best antihistamine for cat allergies

How To Reduce Animal Allergens

Pet allergens can remain in the carpets and furniture, and can even linger in the air, for up to six months. To help reduce allergens:

  • Your cat or dog should be bathed at least once per week.
  • Vacuum or clean your floors often, and wear a dust mask when doing it.
  • In rooms that your pet is most active, you might consider running an HEPA filter-equipped air purifier.
  • Pets should be kept off carpets and upholstered furniture, as well as out of bedrooms.
  • Don’t pet, hug, or kiss animals that have allergens. Wash your hands immediately with soap and warm water if you are allergic to any of these allergens.
  • It is a good idea to have someone else brush your pet’s fur.


For cats with persistent symptomatic pruritus, microemulsified Cyclosporine (7 mg/kg/day), is an option to corticosteroids. Multiple mechanisms are involved in Cyclosporine’s action. These include inhibiting T-cell activation, histamine release, cytokine production, survival and degranulation, as well as histamine and histamine release.

Cyclosporine is not yet approved for use on cats as a treatment for allergic skin diseases. However, owners may find it to be an attractive and safe option.

  • You want to minimize the side effects long-term corticosteroids
  • You don’t want to do ASIT.

Cyclosporine therapy has also become a more attractive option for owners due to the introduction of feline Atopica (ah.novartis.us). The liquid formulation provides ease of administration and flexibility in dosing, and it may be administered with food.

best antihistamine for cat allergies

Bestlife4Pets Healthy Skin And Allergy Relief

BestLife4Pets Healthy Skin and Allergy Relief is an all-natural supplement that helps relieve allergies in cats, while strengthening the immune system so it can help fight off allergens in the first place. It helps reduce itching, minor allergic reactions and overall shedding.

The formula reduces patchy balding and swelling as well as raised welts due to allergen exposure. It helps balance hormones and nutrient absorption, so cats can better fight off allergens naturally. It is also known to reduce licking. The downsides are that the pills are bitter, so most cats will not eat them unless they are disguised with other food, and the pills are also large, so they can be tough for some cats to chew and digest even if they are willing to take them as-is.

What Causes Cat Allergies?

About 10% of the U.S. population has pet allergies and cats are among the most common culprits. Two-thirds of cat allergies are the same as those that affect dogs. But contrary to what you might think, it’s not the fur or hair that’s the real problem. Cat allergies can be caused by proteins found in saliva, urine and dander.

What is the cause of such an allergic response in our bodies? People with allergies have oversensitive immune systems. People with allergies mistake harmless substances, such as cat dander, for harmful invaders and attack them like bacteria or viruses. Your body attacks the trigger or allergen and the symptoms are side effects.

Keep in mind that even if you don’t have an actual cat allergy, your cat can still indirectly cause your allergies to flare up. Cats from outside can carry pollen, mold and other allergens onto their fur.

What about “hypoallergenic” cat breeds? While some breeds — like the “hairless” sphinx — are said to be less likely to trigger symptoms of cat allergies than others, any cat has the potential to cause problems. It doesn’t matter what breed it is, how long its hair is, or how many times it sheds. So if you know that you or another family member is allergic to cats, getting one — no matter what the breed — is not a good idea.

  • Sneezing

best antihistamine for cat allergies


For some unfortunate souls, living with cats means frequent sneezing, watery eyes, runny noses and wheezing. In severe cases, cat allergies can exacerbate asthma, notes the journal Environmental Health Perspectives. Living with cat allergies can be a misery, but living without that little bundle of purring love? Well, that’s not an option, either. So how can people who suffer from cat allergies remain in relative comfort while living with a kitty?

If you are allergic to cats and have to live with them, it will be easier for you to keep a few cat allergy remedies on hand. Continue reading to find out how you can choose the best cat companion for your family, keep your house clean and take routine care of your pet.

What Is Flea Allergy And How Is It Treated?

The most frequent allergy among cats is flea allergy.

Fleabite reactions can cause minor irritation for normal cats, contrary to common belief. On the other hand, a cat with flea allergies has a severe reaction to even a single fleabite. This reaction is an allergic response to proteins or antigens present in the flea’s saliva. Some of the flea saliva can be injected into skin by biting a cat for consuming a blood meal. One fleabite can cause severe itching in cats, leading to excessive scratching and chewing. There will often be open sores or scabs on the skin, resulting in a secondary bacterial skin infection (pyoderma). The area most commonly involved is over the rump or base of the tail. In addition, the cat may have numerous small scabs around the head and neck. These scabs are often referred to as miliary dermatitis, a term that was coined because the scabs look like millet seeds (see handout “Miliary Dermatitis in Cats” for more information on this skin condition).

Flea allergies can be caused by flea saliva. Therefore, it is important to avoid fleabites. Flea infestations are most common in warmer climates, but they can also occur throughout the year. Strict flea control is the foundation of successful treatment. Many flea treatments are highly effective, whether they’re used to treat the cat or control the environment. (For more information, please see the handout, “Flea Control in Cats”. Modern flea prevention products make it much easier to keep fleas away from your cat’s skin.

The use of corticosteroids, also known as steroids or cortisone, can be effective in blocking allergic reactions and providing immediate relief for cats suffering from severe itching due to flea allergy. This is often a necessary part of treatment especially during the initial stages. If a secondary bacterial skin infection occurs from the flea allergy dermatitis, appropriate antibiotics must be used, generally for two to four weeks. See handout “Flea Allergy Dermatitis in Cats” for more detailed information about flea allergies in cats.

best antihistamine for cat allergies

What is Inhalant Allergy or Atopy?

Inhalant allergy or atopy is not well understood in cats. Atopic Dermatitis is a condition that causes allergic reactions in humans and dogs to pollens and molds.

Many of these allergies occur seasonally, such as ragweed, cedar, and grass pollens. Others, however, are always with us, like molds, mildew and house dust mites. These allergens can be inhaled by humans, causing a condition known as allergy. In humans, atopy is also sometimes called ‘hay fever’. Atopy in cats is characterized by severe and generalized itching.

Most cats that have an inhalant allergy are allergic to several allergens. Itching that is seasonal or small in number may only last for a couple of weeks. If the number of allergens is large or they are present year-round, the cat may itch constantly.

Keep your pet safe

If you keep your pet, you can help minimize the allergens in your home with these tips:

  • Regularly bathe your pet. Ask a family member or friend without allergies to bathe your pet on a weekly basis.
  • Establish a pet-free zone. To reduce allergens in certain areas of your home, like your bedroom, make it pet-free.
  • Remove carpeting and dander-attracting furnishings. Replace wall-to-wall carpeting by tile, wood or linoleum. Vinyl flooring won’t trap pet allergens. Consider replacing other allergen-attracting furnishings, such as upholstered furniture, curtains and horizontal blinds.
  • Enlist help. When it comes time to clean your pet’s kennel, litter box or cage, ask a family member or friend who doesn’t have pet allergies to do the work.
  • High-efficiency filters are recommended. High-efficiency particulate air (HEPA) air purifiers and vent filters may help reduce airborne pet allergens.
  • Keep your pet outside. You can make your house less allergenic if your pet is able to live outside. This option isn’t appropriate for many pets or in certain climates.

best antihistamine for cat allergies

Issues If You Have Asthma

If you have already been diagnosed with asthma and you are having difficulty managing the disease, your doctor may talk to you about the possibility of allergies. Although allergies are a major contributing factor to asthma, the influence of allergy on asthma isn’t always obvious.

Because pollen allergies are seasonal, the effects of them can be quite noticeable. For example, you may have more difficulty managing your asthma for a short time during the summer.

A pet you are exposed to all year can cause allergy. Even if you don’t have a pet, you may be exposed to pet allergens in other people’s homes or that have been transported on people’s clothes at work or school. You may overlook allergy as an issue that could complicate your asthma, but it might be the primary reason.

Biologicvet Bioskin&Coat Powder — Premium Choice

This antihistamine formula offers relief for cats with seasonal allergies and hotspots or yeast overgrowth throughout the year. Natural ingredients such as lignan rich biofiber and lignan-rich biofiber optimize nutrients absorption for spayed cats. This also enhances hormone function. The formula was made in America and meets all National Animal Supplement Council requirements.

You don’t have to worry about artificial colors or flavors. And because there are no binders in the formula, your cat can be sure that it will receive a balanced dose. This formula includes real ingredients, like sunflower and sesame seeds, flax, and natural prebiotics, to replenish nutrients and help the immune system fight off allergy attacks. This option comes at a higher price than others and must be stored in a safe manner to preserve its integrity.

best antihistamine for cat allergies

#1 Best Antihistamine Gel Cap: Allegra Allergy 24 Hour Gel Caps (Fexofenadine)

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Fexofenadine, which is second-generation antihistamine, reduces symptoms such as sneezing and runny noses, itching, fatigue, and itchiness.

Compared to sedating first-generation antihistamines, the drug has a limited ability to cross the blood-brain barrier. It is therefore not drowsy. Adult patients are most likely to experience a headache.

It’s sold under the brand name Allegra, but has been available as a generic drug since 2011.

This product is in a gel cap form, making it easy to swallow. It’s a fast-acting formula that starts producing results within an hour of dosage. The effects of the formula last up to 24 hours, providing you with a full day of protection.

It’s appropriate for people age 12 and over. Each gel cap offers 180mg fexofenadine.


Antihistamines alone may be useful for mild pruritus (particularly atopy), but are most useful as part of combination therapy, such as use with fatty acids, to reduce the amount of corticosteroid required.

As in humans, failure to respond to one antihistamine does not mean the patient will not respond to another one. It may be necessary to formulate an antihistamine trial, in which the owner tries different antihistamines for 2 weeks each in order to find one that may provide some relief.

best antihistamine for cat allergies

Which over-the-counter antihistamines are safe for cats?

  • PetMD Editorial – Cats suffering from colds can be treated at the home.
  • PetMD Editorial – Safe and effective human medications for pets with serious illnesses
  • Matthew Everett Miller DVM explains why my cat has a tendency to sneeze.
  • A review of kidney failure in cats by PetMD.
  • Here are some common home remedies for cats…
  • Here are 5 herbs that can relieve cat stress.

What is the Work of Allergy Medications?

The body reacts to allergens by producing histamine.

Many allergy symptoms can be caused by histamine, such as inflammation of the sinuses or skin, redness and pain.

Immune responses also encourage extra mucus to develop, which helps to clear allergens from the nose and throat.

Histamine reactions are blocked by allergy medications. This dulls the body’s response to minor or harmless allergens, such as pollen, dust, and pet dander.

best antihistamine for cat allergies

Types Of New-Generation Antihistamine Medications For Cat Allergies:

  • Loratidine (Claritin)
  • Cetirizine (Zyrtec)
  • Levocetirizine (Xyzal)
  • Fexofenadine, Allegra and Aller-ease
  • Nasal Steroid Sprays

Corticosteroids are not to be confused for the likely anabolic steroids that your brother-in-law uses. They target inflammation to reduce allergy symptoms.

Nasal steroid sprays fight the stuffiness, itching, and runniness that make you and your nose miserable. Nasal steroids can make sensitive people’s noses feel worse. Side effects are rare, but they include nosebleeds and, ironically, runniness.

What Over-The-Counter Medicine Is Good For Cat Allergies?

In addition to antihistamines, such as diphenhydramine (Benadryl), loratadine (Claritin) or cetirizine (Zyrtec), nasal sprays containing fluticasone (Flonase) or mometasone (Nasonex) may It may reduce symptoms and prevent the release of immune system chemicals.

best antihistamine for cat allergies

Lifestyle And Home Remedies

Avoiding exposure to pets is the best remedy for pet allergy. This may not be an option for many because their family is often attached to their pet. Talk to your doctor about whether reducing exposure to your pet, rather than finding a new home for your pet, may be sufficient for managing your pet allergy.

The Things We Didn’t Like

  • Contains sucralose and sorbitol, which are controversial artificial sweeteners
  • Sucralose and Sorbitol are two controversial artificial sweeteners.

best antihistamine for cat allergies

Allegra Allergy 24-Hour Gel Caps

Product Info

  • This fast-acting formulation provides immediate relief for allergy symptoms within one hour.
  • Continues to minimize allergy symptoms for 24 hours after you take the capsule
  • Gel caps are easy to dose and swallow
  • Extraordinarily non-drowsy
  • One of the more expensive antihistamines on the market


Prednisone is not converted to prednisolone by cats. Prednisolone and methylprednisolone should be used only in cats. Although oral triamcinolone and dexamethasone are acceptable for short-term use in cats, a recent study supports that dexamethasone had higher diabetogenic effects compared to prednisolone.6

best antihistamine for cat allergies

What Causes Pet Allergies?

Many people suffer from animal allergies due to proteins in the animal’s fur or skin cells that can fall off. Any time of the year, pet dander may cause allergic reactions. This is especially true during winter when many people spend less time outdoors. If you think you might have an animal allergy, see an allergist for confirmation.

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